Perforation of the skin provokes the formation of controlled skin damage, which activates repairing processes stimulating the synthesis of connective tissue support fibers (dermis). As a result of micro punctures inflammation and vascular angiogenesis are initiated, thanks to which the skin visibly smoothest and its metabolism and oxygenation increases. The formation of skin microchannels also facilitates the absorption and transport of active substances applied externally to the skin. Thanks to its multidimensional action, mesopenONE™ causes thickening of the skin and enables its strong conditioning.